ADCC Reporter Bioassay, F Variant, Core Kit Technical Manual
Instructions for Use of Product(s)
G9790, G9798
Literature # TM427
The ADCC Reporter Bioassay, F Variant, is a bioluminescent reporter assay for quantifying biological activity on pathway activation by therapeutic antibodies in an ADCC mechanism of action (MOA) assay. The assay combines a simple, add-mix-read format and an optimized protocol to provide a bioassay that has low variability and high accuracy. Moreover the bioassay can be performed in a single day. These performance characteristics make the bioassay suitable for application across antibody drug research and development. The thaw-and-use cells provided in the ADCC Reporter Bioassay, Variant, Core Kits are generated under highly controlled conditions that drive low assay variability run to run, while providing the convenience of an assay reagent that eliminates the need to propagate cells each time.
Summary of Changes
The following changes were made to the 8/19 revision of this document:
1. Figures 9 and 10 were updated.
2. Section 8. Related Products was updated.
Printed in USA. Revised 8/19