Caspase Inhibitor Z-VAD-FMK
A Cell-Permeant Pan Caspase Inhibitor of Apoptosis
- Irreversibly binds to catalytic site of caspase proteases
- Provided in DMSO for convenient addition to cell culture or extracts
Catalog Number:
Size
Catalog Number: G7231
Catalog Number: G7232
Z-VAD-FMK (carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone) is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. For inhibition of apoptosis, Z-VAD-FMK should be added at the same time that apoptosis is induced. Z-VAD-FMK is provided at 20mM in DMSO for convenient addition to cell culture or extracts. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. The suggested concentration for use in the anti-Fas mAb-treated Jurkat cell culture model system is 20μM.
For more information, see the Protocols & Applications Guide.
Protocols
No protocols available
Specifications
Catalog Number:
What's in the box?
| Item | Part # | Size |
|---|---|---|
|
Caspase Inhibitor Z-VAD-FMK |
G723B | 1 × 50μl |
SDS
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Use Restrictions
For Research Use Only. Not for Use in Diagnostic Procedures.Storage Conditions
What's in the box?
| Item | Part # | Size |
|---|---|---|
|
Caspase Inhibitor, Z-VAD-FMK |
G723A | 1 × 125μl |
SDS
Search for SDSCertificate of Analysis
Use Restrictions
For Research Use Only. Not for Use in Diagnostic Procedures.Storage Conditions
Resources
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